hsa-miR-191 Is a Candidate Oncogene Target for Hepatocellular Carcinoma Therapy
نویسندگان
چکیده
منابع مشابه
hsa-miR-191 is a candidate oncogene target for hepatocellular carcinoma therapy.
Hepatocellular carcinoma (HCC) is generally a fatal disease due to a paucity of effective treatment options. The identification of oncogenic microRNAs that exert pleiotropic effects in HCC cells may offer new therapeutic targets. In this study, we have identified the human microRNA miR-191 as a potential target for HCC therapy. Inhibition of miR-191 decreased cell proliferation and induced apop...
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Hepatocellular carcinoma (HCC) is a relevant health problem, being the sixth most common cancer worldwide in terms of incidence with 626,200 new cases per year, accounting for 5.7% of all new cancer cases. Due to the poor prognosis of the disease, the number of deaths per year is almost the same as new cases (598,000), making HCC the third most common cause of cancer-related death. Prognosis an...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2010
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-10-1313